Yazar "Taskin, Eylem" için listeleme
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Acute adriamycin-induced cardiotoxicity is exacerbated by angiotension II
Taskin, Eylem; Kindap, Elvan Kunduz; Ozdogan, Kalender; Aycan, Mukerrem Betul Yerer; Dursun, Nurcan (SPRINGER, 2016)Adriamycin (ADR) increases the production of reactive oxygen species (ROS), which diminishes mitochondrial function. Angiotensin-II stimulates mitochondrial ROS generation. The aim of the study was to examine whether ... -
Counteraction of Apoptotic and Inflammatory Effects of Adriamycin in the Liver Cell Culture by Clinopitolite
Yapislar, Hande; Taskin, Eylem; Ozdas, Sule; Akin, Demet; Sonmez, Emine (HUMANA PRESS INC, 2016)Growing evidence has been reported on adriamycin (ADR) hepatotoxicity in literature. Hepatotoxicity caused by the use of drugs has a serious undesirable effect in the cure of cancer patients that needs to be eliminated. ... -
Inhibition of Angiotensin-II Production Increases Susceptibility to Acute Ischemia/Reperfusion Arrhythmia
Taskin, Eylem; Tuncer, Kadir Ali; Guven, Celal; Kaya, Salih Tunc; Dursun, Nurcan (INT SCIENTIFIC LITERATURE, INC, 2016)Background: Myocardial ischemia and reperfusion lead to impairment of electrolyte balance and, eventually, lethal arrhythmias. The aim of this study was to investigate the effects of pharmacological inhibition of angiotensin-II ... -
Low dose monoethyl phthalate (MEP) exposure triggers proliferation by activating PDX-1 at 1.1B4 human pancreatic beta cells
Guven, Celal; Dal, Fulya; Ahbab, Mufide Aydogan; Taskin, Eylem; Ahbab, Suleyman; Cinar, Suzan Adin; Akcakaya, Handan (PERGAMON-ELSEVIER SCIENCE LTD, 2016)Phthalate plasticizers used in a wide range of common plastic products are released into the environment and may pose a risk of increased incidence of type 2 diabetes. In this work, we studied the effects of monoethyl ... -
Protective Effect of Quercetin Against Oxidative Stressinduced Toxicity Associated With Doxorubicin and Cyclophosphamide in Rat Kidney and Liver Tissue
Kocahan, Sayad; Dogan, Zumrut; Erdemli, Erman; Taskin, Eylem (IRANIAN SOC NEPHROLGY, 2017)Introduction. Doxorubicin and cyclophosphamide are widely used anticancer drugs with substantial toxicity in noncancerous tissue resulting from oxidative damage. Quercetin is a potent antioxidant compound. We hypothesized ... -
The restoration of kidney mitochondria function by inhibition of angiotensin-II production in rats with acute adriamycin-induced nephrotoxicity
Taskin, Eylem; Ozdogan, Kalender; Kindap, Elvan Kunduz; Dursun, Nurcan (TAYLOR & FRANCIS LTD, 2014)Adriamycin (ADR) is commonly used for many solid tumor treatments. Its clinical utility is, however, largely limited by the adverse reactions, are known to be nephrotoxic. The mechanism by which it induces kidney damage ...